虫草素抗肿瘤活性研究进展

王征,武雪,刘建利,唐志书

中国药学杂志 ›› 2015, Vol. 50 ›› Issue (16) : 1365-1368.

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中国药学杂志 ›› 2015, Vol. 50 ›› Issue (16) : 1365-1368. DOI: 10.11669/cpj.2015.16.001
综述

虫草素抗肿瘤活性研究进展

  • 王征1,武雪3,刘建利2,唐志书1*
作者信息 +

Advances in Research on Antitumor Activities of Cordycepin

  • WANG Zheng1, WU Xue3, LIU Jian-li2, TANG Zhi-shu1*
Author information +
文章历史 +

摘要

虫草素是我国传统名贵中药材冬虫夏草及北虫草中的主要活性成分之一,具有多种药理活性。笔者经查阅国内外文献,将虫草素对白血病细胞、肺癌、肝癌、前列腺癌、宫颈癌、结肠癌、睾丸间质瘤、人胶质瘤及甲状腺癌等多种肿瘤细胞生长增殖的抑制作用及其分子生物学机制进行综述。为后续更全面深入地研究虫草素抗肿瘤活性及其分子生物学机制奠定了基础。

Abstract

Cordycepin is a main active constituent of the famous traditional Chinese medicines Cordyceps sinensis and Cordyceps militaris. The antitumor activities and molecular mechanism of cordycepin on leukemia cells, lung cancer cells, hepatoma cells, prostatic carcinoma cells, cervical-cancer cells, colon cancer cells, leydig tumor cells, glioma cells and thyroid carcinoma cells were summarized.

关键词

虫草素 / 抗肿瘤 / 分子机制

Key words

cordycepin / antitumor activity / molecular mechanism

引用本文

导出引用
王征,武雪,刘建利,唐志书. 虫草素抗肿瘤活性研究进展[J]. 中国药学杂志, 2015, 50(16): 1365-1368 https://doi.org/10.11669/cpj.2015.16.001
WANG Zheng, WU Xue, LIU Jian-li, TANG Zhi-shu. Advances in Research on Antitumor Activities of Cordycepin[J]. Chinese Pharmaceutical Journal, 2015, 50(16): 1365-1368 https://doi.org/10.11669/cpj.2015.16.001
中图分类号: R284   

参考文献

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基金

国家自然科学基金资助项目(81373978)
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